Bioinformation - Beyond Bioinformatics: It is free, open access and online immediately upon acceptance.

Bioinformation is an online journal publishing research articles in biological knowledge discovery after full peer review.

Bioinformation is added in DOAJ and listed in HIWW. All articles are published, without barriers to access, immediately upon acceptance. The abstracts of published papers will be indexed in major indexing databases after the completion of one year from the launch date.

Bioinformation publishes original research articles in all aspects of biological knowledge discovery through mathematical and computational analysis of biological data. The journal specifically invites articles describing new biological insights based on primary or derived data. This has been added to Biological Informatics Subject Tracer Information Blog.

Towards in silico prediction of immunogenic epitopes.

Flower DR.

Edward Jenner Institute for Vaccine Research, Compton, RG20 7NN, Berkshire, UK.  darren.flower at jenner.ac.uk

As torrents of new data now emerge from microbial genomics, bioinformatic prediction of immunogenic epitopes remains challenging but vital. In silico methods often produce paradoxically inconsistent results: good prediction rates on certain test sets but not others. The inherent complexity of immune presentation and recognition processes complicates epitope prediction. Two encouraging developments - data driven artificial intelligence sequence-based methods for epitope prediction and molecular modeling methods based on three-dimensional protein structures - offer hope for the future.

Publication Types:
Review
Review, Tutorial