pandemic

Bird flu viruses would have to make at least two simultaneous genetic mutations before they could be transmitted readily from human to human, according to research published today in PLoS ONE.
The authors of the new study, from Imperial College London, the University of Reading and the University of North Carolina, USA, argue that it is [...]

Drug companies and nonprofit organizations are joining forces to develop new drugs and vaccines to target so-called “neglected” diseases that claim millions of lives in the developing world each year. Those hard-to-treat diseases include malaria, tuberculosis, dengue fever, and other conditions. That’s the topic of the cover story scheduled for the current issue of Chemical [...]

Globalisation and industrialisation are causing diseases to spread from humans to animals, a study has shown.
Researchers from The Roslin Institute of the University of Edinburgh have shown that a strain of bacteria has jumped from humans to chickens.
It is believed to be the first clear evidence of bacterial pathogens crossing over from humans to animals [...]

The devastation of the 1918-1919 influenza pandemic is well known, but a new article suggests a surprising factor in the high death toll: the misuse of aspirin. Appearing in the November 1 issue of Clinical Infectious Diseases and available online now, the article sounds a cautionary note as present day concerns about the novel H1N1 [...]

The anticipated onset of a second wave of the H1N1 influenza pandemic could present a host of thorny medical ethics issues best considered well in advance, according to the University of Toronto Joint Centre for Bioethics, which today released nine papers for public discussion.
Topics include duty of health care workers to work during a serious [...]

A new iPhone application, created by researchers at Children’s Hospital Boston in collaboration with the MIT Media Lab, enables users to track and report outbreaks of infectious diseases, such as H1N1 (swine flu), on the ground in real time. The application, “Outbreaks Near Me,” builds upon the mission and proven capability of HealthMap, an online [...]

Walter and Eliza Hall Institute scientists have created a weakened strain of the malaria parasite that will be used as a live vaccine against the disease. The vaccine, developed in collaboration with researchers from the US, Japan and Canada, will be trialled in humans from early next year.
Malaria kills more than one million people each [...]

A novel vaccine strategy using virus-like particles (VLPs) could provide stronger and longer-lasting influenza vaccines with a significantly shorter development and production time than current ones, allowing public health authorities to react more quickly in the event of a potential pandemic.
Ted Ross, Ph.D., an assistant professor at the University of Pittsburgh’s Center for Vaccine Research, [...]

A recent study by University of Maryland researchers examines the mechanisms underlying transmission of combined avian-human viruses and illustrates how virus outbreaks like that of the current swine flu come about. The study suggests that the ease with which a dangerous avian influenza virus can cause a human flu pandemic may be greater than [...]

Researchers at The Scripps Research Institute in La Jolla, California, supported in part by the National Institutes of Health, have identified a common Achilles’ heel in a wide range of seasonal and pandemic influenza A viruses. The study found an infection-fighting protein, or human antibody, that neutralizes various influenza A virus subtypes by attaching to [...]

It’s as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria — one of the world’s most pressing public health problems.
The resistant nasty pathogens cause thousands of deaths each [...]

Few things sting like a mosquito’s bite — especially if that bite carries a disease such as malaria, yellow fever, Dengue fever or West Nile virus. But if researchers from The University of Arizona in Tucson have their way, one day mosquito bites may prove deadly to the mosquitoes as well.
“Our goal is to turn [...]